3D-printed tumors represent a significant advancement in cancer research, offering a more relevant model compared to traditional 2D cell cultures and animal models. By mimicking the complex architecture and microenvironment of human tumors, these models enable researchers to study cancer biology in a context that closely resembles human disease. This can lead to a better understanding of tumor heterogeneity, and treatment resistance, ultimately informing the development of more effective therapies.
In this application note, we present data demonstrating the similarities between a donor lung tumor tissue and Carcinotech’s 3D-bioprinted lung tumor in terms of both cellular composition and response to drug treatment. These findings highlight the potential of 3D-bioprinted models as translational tools for pre-clinical research and drug development.