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Tumor Models

Accelerate the Path to Treatment Breakthroughs

Carcinotech expertly captures the complexities of cancer by creating patient-derived, 3D tumors providing a powerful tool for cancer research.
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The Next Generation of 3D Cancer Models are Here

Current cancer models often fail to replicate tumor biology, resulting in poor drug predictability and high clinical trial failure rates.

Carcinotech addresses these challenges with advanced, precisely engineered models that closely mimic the phenotypic characteristics of in vivo tumors. Our models are highly reproducible and provide clinically predictive insights to better bridge the gap between research and successful clinical outcomes.

Carcinotech’s Cancer Models Compared to Tumor Organoids

Current tumor organoid models are simplistic, using few cell types and lacking uniformity. Carcinotech overcomes these issues with automated bioprinting, tailored matrices, and the inclusion of over 20 patient-derived cell types. This results in precise, reproducible 3D models that mimic native tumor biology and its complex microenvironment.
Monocyte
Macrophage
Cancer Associated Fibroblast
Extracellular Matrix
Cancer Stem Cell
Cancer Cell
T-cell
B-cell
Natural Killer cell
Endothelial cell
Tumor Organoid
Depicting three smaller tumor organoids from a singular well of a 24-well plate.
Carcino3DTM Tumor
A single large 3D tumoroid with ECM from a 96-well plate.

Fulfilling the Need for More Accurate and Representative Cancer Models

Tumor Organoids

(Dissociated Tissue Derived Models)

Carcino3D™ Tumor
PDX Models

(Humanized Mice Models with Orthotopic Engraftment)

TME Complexity Low to moderate High High
Tumor Infiltrating Immune Cells
Tumor Heterogeneity Low High High
Uniformity Across Individual Models
Model Development Time 12 weeks 6-12 weeks 12-24 weeks
Stromal cells present
Cost Low Moderate High
Ethical

Application Note

Carcino3D™ GBM Model
Discover how our Carcino3D™ GBM model accurately replicates the genetic profile of the parental tumor biopsy, demonstrates effective responses to standard-of-care drug treatments, and functions as a high-throughput platform for screening multiple therapeutic modalities.
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A Translational 3D Cancer Tool for Use Across the Drug Development Lifecycle

Our robust models are invaluable tools for both early drug discovery and preclinical efficacy testing.

Frequently Asked Questions

We can create 3D tumor models for any solid tumor, given access to a patient sample. Our expertise includes developing models for various cancer types, such as lung, breast, brain, colorectal, pancreatic and ovarian cancers.
Our models are modality agnostic. We can support with drug development and testing of immunotherapies, cancer vaccines, radioimmunotherapies, monoclonal antibodies, targeted therapies, chemotherapies, hormone therapies, oncolytic virus therapies and gene therapies.

Ready to Transition Carcinotech’s 3D Tumor Models?

Speak to our team for insights and expertise on navigating the shift from conventional research tools.
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